Midlife Weight Gain: Understanding the Biology and Finding Solutions
- Dr. Rochelle Bernstein

- Mar 5
- 4 min read
Updated: Mar 5
Midlife is a time of profound change, especially for women. Between the ages of 40 and 65, hormonal shifts, aging, and lifestyle factors converge, making weight gain a common challenge. Although aging is the primary driver, menopause plays a critical role in redistributing fat, often increasing abdominal fat. This shift not only affects appearance but also raises the risk of chronic health conditions, including heart disease, diabetes, and certain cancers. Understanding the biological mechanisms behind midlife weight gain is essential for developing effective strategies to maintain health and well-being.
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