What role does progesterone play in managing menopausal symptoms?

Progesterone is a hormone made by a woman's ovaries, adrenal gland, and, during pregnancy, the placenta. It is the most important of a group of steroid hormones called the progestogens. Menopausal women experience a significant decrease in their progesterone level, which is important since natural progesterone improves pain tolerance, alleviates joint pain, and provides relief from anxiety. Progesterone also plays a crucial role in bone health by reducing the rate of bone absorption and minimizing calcium loss in urine. Additionally, it has a calming effect on the brain, promoting anti-anxiety responses. Menopausal women have a higher risk of ACL and MCL tears in their knees as well as shoulder injuries because progesterone stabilizes tendons and ligaments.

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